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atcc 35822 isoniazid resistant  (ATCC)


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    ATCC atcc 35822 isoniazid resistant
    Atcc 35822 Isoniazid Resistant, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 28 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/isoniazid+resistant/Mycobacterium+tuberculosis/pm40393139-51-8-8
    Average 94 stars, based on 28 article reviews
    atcc 35822 isoniazid resistant - by Bioz Stars, 2026-09
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    other:

    Article Title: Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes
    Article Snippet: M. tuberculosis strains H37Rv (ATCC 27294), four monoresistant variants of M. tuberculosis H3Rv, including isoniazid-resistant (ATCC 35822), streptomycin-resistant (ATCC 35820), rifampicin-resistant (ATCC 35838), and ethambutol-resistant (ATCC 35798), and two MDR clinical isolates of M. tuberculosis (CIBIN/UMF15:99 and SIN 4) were employed as mycobacterium testing organisms.

    Article Title: Comparative evaluation of the nitrate reduction assay, the MTT test, and the resazurin microtitre assay for drug susceptibility testing of clinical isolates of Mycobacterium tuberculosis.
    Article Snippet: Reference strains H37Rv (ATCC 27294), and rifampicin-resistant (ATCC 35838), isoniazid-resistant (ATCC 35822), ethambutol-resistant (ATCC 35837) and streptomycin-resistant (ATCC 35820) strains from the American Type Culture Collection, were used as susceptible and resistant controls.

    Article Title: 1,3-Azoles from ortho-naphthoquinones: synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis.
    Article Snippet: The minimum inhibitory concentrations (MIC) for all of the compounds were evaluated against M. tuberculosis H37Rv (pansusceptible), rifampicin-resistant (RIFr, ATCC 35338) and isoniazid-resistant (INHr, ATCC 35822) strains (Table 1).

    Activity Assay:

    Article Title: Imidazoles and Oxazoles from Lapachones and Phenanthrene-9,10-dione: A Journey through their Synthesis, Biological Studies, and Optical Applications.
    Article Snippet: Diverse structural frameworks are found in natural compounds and are well known for their chemical and biological properties; such compounds include the imidazoles and oxazoles.. Researchers worldwide are continually working on the development of methods for synthesizing new molecules bearing these basic moiety and evaluating their properties and applications.. To expand the knowledge related to azoles, this review summarizes important examples of imidazole and oxazole derivatives from 1,2-dicarbonyl compounds, such as lapachones and phenanthrene-9,10-diones, not only regarding their synthesis and biological applications but also their photophysical properties and uses.

    Article Title: Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment
    Article Snippet: .. The antimycobacterial activity of the triterpenic acids was evaluated against the M. tuberculosis H37Rv (ATCC 27294) reference strain (a pan-sensitive strain) and against four monoresistant strains of M. tuberculosis H37Rv [streptomycin-resistant (ATCC 35820), isoniazid-resistant (ATCC 35822), ethambutol-resistant (ATCC 35837) and rifampicin-resistant (ATCC 35838)]. .. The microorganisms were cultured up to log phase growth at 37°C in Middlebrook 7H12 broth supplemented with 0.2% glycerol and enriched with 10% Oleic acid-albumin, dextrose and catalase (OADC) and further diluted to 1:20.

    Article Title: Imidazole and its derivatives as potential candidates for drug development
    Article Snippet: .. These compounds were tested for TB analysis against the M. tuberculosis H37Rv (pansusceptible), rifampicin-resistant (RIFr, ATCC 35338) and isoniazid-resistant (INHr, ATCC 35822) strains of bacteria among them the compounds with imidazole units showed good to moderate activity against these strains (Moura et al., 2012). ..

    Bacteria:

    Article Title: Imidazole and its derivatives as potential candidates for drug development
    Article Snippet: .. These compounds were tested for TB analysis against the M. tuberculosis H37Rv (pansusceptible), rifampicin-resistant (RIFr, ATCC 35338) and isoniazid-resistant (INHr, ATCC 35822) strains of bacteria among them the compounds with imidazole units showed good to moderate activity against these strains (Moura et al., 2012). ..



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    MICs of Homo-BacPROTACs and monomers against clinical isolates resistant to single Mtb drugs

    Journal: Nature Communications

    Article Title: Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria

    doi: 10.1038/s41467-024-46218-7

    Figure Lengend Snippet: MICs of Homo-BacPROTACs and monomers against clinical isolates resistant to single Mtb drugs

    Article Snippet: The different Mtb strains used were drug-sensitive strains (H37Rv ATCC 27294 and 11291), mono drug resistant strains Isoniazid resistant H37Rv (katG del ) ATCC 35822 , Rifampicin resistant H37Rv (rpoB S450L ) ATCC 35838 , moxifloxacin resistant H37Rv clinical isolate FNDR-M1 as well as multidrug resistant strains (ATCC 35825 and 8673) with drug-resistance against 1st and 2nd-line anti-TB drugs.

    Techniques:

    a , b Exit vector 6-based Homo-BacPROTACs 7 and 8 (UdSBI-0545), as well as exit vector 7-based Homo-BacPROTACs 11 and 12 (UdSBI-4377) were assessed in a 4- and 7-day incubation on THP-1 macrophages following infection with Mtb H37Rv. The Homo-BacPROTACs were compared to their corresponding monomers ( 5 for exit vector 6 and 10 for exit vector 7) and the reference antibiotics rifampicin and moxifloxacin, which are known to inhibit the intracellular propagation of Mtb H37Rv. Exit vector 6 Homo-BacPROTACs showed a more efficient concentration-dependent reduction of cfu/ml over time with an E max of 1.22 − 1.27 at 50 µM, as compared to exit vector 7 based Homo-BacPROTACs or matched monomers. The various compound concentrations are indicated in different colours, matching across the panels. CC means Mtb culture control, where no drug treatment was given. For further details see text. Error bars indicate mean ± SD of n = 2 well replicates. The CC, rifampicin and moxifloxacin values were taken as common reference points in the various graphs. Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria

    doi: 10.1038/s41467-024-46218-7

    Figure Lengend Snippet: a , b Exit vector 6-based Homo-BacPROTACs 7 and 8 (UdSBI-0545), as well as exit vector 7-based Homo-BacPROTACs 11 and 12 (UdSBI-4377) were assessed in a 4- and 7-day incubation on THP-1 macrophages following infection with Mtb H37Rv. The Homo-BacPROTACs were compared to their corresponding monomers ( 5 for exit vector 6 and 10 for exit vector 7) and the reference antibiotics rifampicin and moxifloxacin, which are known to inhibit the intracellular propagation of Mtb H37Rv. Exit vector 6 Homo-BacPROTACs showed a more efficient concentration-dependent reduction of cfu/ml over time with an E max of 1.22 − 1.27 at 50 µM, as compared to exit vector 7 based Homo-BacPROTACs or matched monomers. The various compound concentrations are indicated in different colours, matching across the panels. CC means Mtb culture control, where no drug treatment was given. For further details see text. Error bars indicate mean ± SD of n = 2 well replicates. The CC, rifampicin and moxifloxacin values were taken as common reference points in the various graphs. Source data are provided as a Source Data file.

    Article Snippet: The different Mtb strains used were drug-sensitive strains (H37Rv ATCC 27294 and 11291), mono drug resistant strains Isoniazid resistant H37Rv (katG del ) ATCC 35822 , Rifampicin resistant H37Rv (rpoB S450L ) ATCC 35838 , moxifloxacin resistant H37Rv clinical isolate FNDR-M1 as well as multidrug resistant strains (ATCC 35825 and 8673) with drug-resistance against 1st and 2nd-line anti-TB drugs.

    Techniques: Plasmid Preparation, Incubation, Infection, Concentration Assay, Control

    Structure-activity relationships of monomeric dCym derivatives and Homo-BacPROTACs

    Journal: Nature Communications

    Article Title: Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria

    doi: 10.1038/s41467-024-46218-7

    Figure Lengend Snippet: Structure-activity relationships of monomeric dCym derivatives and Homo-BacPROTACs

    Article Snippet: The different Mtb strains used were drug-sensitive strains (H37Rv ATCC 27294 and 11291), mono drug resistant strains Isoniazid resistant H37Rv (katG del ) ATCC 35822 , Rifampicin resistant H37Rv (rpoB S450L ) ATCC 35838 , moxifloxacin resistant H37Rv clinical isolate FNDR-M1 as well as multidrug resistant strains (ATCC 35825 and 8673) with drug-resistance against 1st and 2nd-line anti-TB drugs.

    Techniques: Permeability